Purpose: To combine the resources, infrastructures, and research strengths of multiple countries in order to address transmission of antibiotic resistance following a ‘One Health Approach’.

Scope:

Research should investigate:

       - Selection of resistance and its transmission between individuals and between human and non-human sources

       - The success of clones, organisms, and resistance patterns and the role of different genetic elements

       - The fitness of the resistant bacteria in clinical, community, veterinary, and environmental settings

Research in the following areas are needed:

       - Quantitative multilevel modelling to understand the dissemination of AMR between different environments

       - Risk assessment studies to estimate which transmission pathways from the environment (indoor and outdoor) and/or animals to humans        are the most important to control in order to minimise the transfer of resistant organisms.

       - Explore potential interventions and mitigation strategies, including new strategies, which minimise the emergence, transmission, and/or        exposure risk of resistance in clinical, veterinary, community and environmental settings in a cost-effective, sustainable way.

Following sub-topics are not in the purpose of the call:

       - Development of new antimicrobial drugs that select less for resistance or block transmission

       - Development or testing of diagnostic tools to monitor selection or transmission of AMR

Eligibility: Each transnational consortium submitting a proposal must involve:

       -

       - A minimum of three eligible partners from three different countries

       - A maximum of six project participants (Consortia including partners from countries that are to date underrepresented in the JPIAMR        funding        scheme - this is, Poland and Latvia - may increase the total number of partners to 7)

       - A maximum of two project participants funded by the same funding organisation

       - Project participants not eligible to be funded cannot be consortium coordinators but may be involved in projects. Nonetheless, the consortia        should always consist of a majority of funded project participants. 

National Eligibility (Instituto de Salud Carlos III):

- The Principal Investigator and all members of the research group must belong to the eligible institution or be affiliated to CIBER, CIBERNED or an IIS.

Excluded personnel as PI:

- Those undergoing a postgraduate training in Health Specialization (MIR, FIR, QIR, BIR, PIR)

- Those undergoing research training (e.g. PhD students, or “Río Hortega” contracts)

- Researchers contracted by a RETIC or a CONSOLIDER

- Those undergoing postdoctoral training (e.g. “Sara Borrell“ or “Juan de la Cierva” contracts)

Funding Scheme:

- 350.000€ for extramural ISCIII

- 150.000€ for intramural ISCIII

Eligible costs:

- Personnel (Only eligible for Coordinators), small equipment (40.000€ per Coordinator, 20.000€ per Partner), travel&allowance (9.000€ per Coordinator, 4.500€ per Partner), consumables, subcontracting and other services (up to 50% of direct costs), overheads (21%)

Incompatibilities: There is no incompatibility with AES 2016

Duration: 3 years

Timeline:

       - VHIR internal deadline: March 4th, 2016

       - Official deadine for pre-proposals: March 21st, 2016 (17:00 CET)

       - Full proposals submission: July 4yh, 2016

       - Final funding decision: By October 15th, 2016

       - Start of funding: end of 2016-beginning of 2017

Further information: JPI-EC-AMR ERA-NET Cofund Call on Transmission Dynamics