The main interest of our Laboratory is the study of molecular events underlying the oncogenic process, especially in colorectal cancer. Colorectal cancer is the second leading cause of cancer related dead in the western world. In 2004 colorectal cancer accounted for approximately 13% of all cancer cases and cancer-related deaths in the European Union, with over 375,000 new cases and more than 200,000 deaths due to this disease. Understanding of the molecular mechanisms underlying the tumorigenic process is a key step that will allow the identification of new markers of prognosis, response to therapy and therapeutic targets. These in turn will lead to an improvement of the survival and quality of life of a large number of patients with colorectal cancer.
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